Theme — ICG as an SLNB Modality
Central question: can indocyanine green, used alone or as the decisive intraoperative step, match or outperform radiocolloid/blue dye for sentinel node detection in melanoma?
Papers
- Vyas et al 2025 - ICG-only SLNB in Head and Neck Melanoma — prospective cohort, 67 patients / 182 nodes; ICG 100% vs radiocolloid 85% vs blue dye 80% detection
- Correspondence Exchange on Vyas et al 2025 — critical letter + author reply
- Duarte-Bateman et al - ICG SLNB Cohort of 1267 Melanoma Patients (JSO) — largest cohort to date; ICG caught nodes radioactivity missed
- Matteucci et al - ICG vs Tc-99m Meta-Analysis — meta-analysis: ICG reliable as adjunct, not full replacement
- Lese et al - Transcutaneous ICG Sensitivity Study — BMI-dependent sensitivity drop
- Red-Capping ICG SLNB Comparative Analysis — 100% detection, ICG alone vs ICG + red-capping
- Reverse Lymphatic Mapping with ICG and Blue Dye - Case Series (No Access) — resource-limited-setting workaround
Where this case fits
Case Overview - Recurrent Truncal Melanoma with Contralateral Axillary SLN adds a data point where ICG’s value was in tracing an aberrant pathway, rather than in a straightforward single-modality replacement of Tc-99m — see Open Questions - ICG Alone vs Complementary Framing.